Natsume has been busy, navigating between humans and Yokai
when he coincidentally reunites with an old classmate, Yuki.
The reunion brings back painful memories of a certain Yokai.
Meanwhile, Natsume also becomes acquainted with Yorie Tsumura,
a woman in the memories of a Yokai whose name Natsume had returned.
Yorie knows much about Reiko, and now lives a peaceful life with her only son, Mukuo.
Interacting with this family is comforting for Natsume,
but a mysterious Yokai has been lurking in their town.

On the way back from investigating, a “Yokai seed” that had latched itself to Nyanko-Sensei
　drops into the Fujiwara Family’s garden and grows overnight into a fruit tree.
When Nyanko-Sensei eats a fruit that is somewhat shaped like himself, he suddenly splits into three!